Guinea pig pancreatic slice in vitro EMAR 3min pulse after 180 min stimulation with 0.01mM carbachol

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Medical Historical Library, Cushing/Whitney Medical Library > Guinea pig pancreatic slice in vitro EMAR 3min pulse after 180 min stimulation with 0.01mM carbachol

15817873

Description

Title: Guinea pig pancreatic slice in vitro EMAR 3min pulse after 180 min stimulation with 0.01mM carbachol
Creator: Jamieson, James D
Contributor: Jamieson, James D
Published / Created: 12/12/1963
Publication Place: New Haven, CT
Publisher: Yale University School of Medicine
Description: 3.25 in. x 4 in. Lantern Slides
These studies showed that the rate of protein synthesis, rate of drainage of the RER to the Golgi and the overall transit rate over the secretory pathway was not accelerated by prior secretagogue release of all preformed zymogen granules. Furthermore, secretory proteins were not rerouted into the cytosol as had been proposed by others.
Extent: 3.25 in. x 4 in.

Access: Public
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Citation: See Jamieson, J. D., and Palade, G.E. Synthesis, intracellular transport, and discharge of secretory proteins in stimulated pancreatic exocrine cells. J. Cell Biol. 50:135-158, 1971.